Guidelines for pharmacologic intervention

Guidelines for pharmacologic intervention 

in postmenopausal women and 

men ≥50 years of age

1.History of hip or vertebral fracture.

2.T-score ≤-2.5 (DXA) at the femoral neck or spine, 

after appropriate evaluation 

to exclude secondary causes.

3.T-score between -1 and -2.5 at the femoral neck or spine, 

and a 10-year probability of hip fracture ≥3 percent or 

a 10-year probability of any major osteoporosis-related fracture ≥20 percent 

based upon the US-adapted WHO algorithm.